![]() The same relationship was observed between TE ratio and GGT ratio ( r = 0.65, P < 0.0001). Correlation between TE ratio and AST ratio ( r = 0.44, P = 0.01) revealed that TE varied proportionally to AST for all patients irrespective of their alcohol status. Final TE was correlated with AST ( r = 0.362, P < 0.05). Evolution of biological data was in accordance with the relapse or abstinent status: abstinence ratio (duration of abstinence/duration follow-up) was correlated with AST ratio ( r = -0.465, P = 0.007) and GGT ratio ( r = -0.662, P < 0.0001). Using 12.5 kPa as cut-off for cirrhosis, 16 patients had cirrhosis at initial TE and 15 patients had cirrhosis at final TE. Using 19.5 kPa as cut-off for cirrhosis, 7 patients had cirrhosis at initial TE and 5 patients had cirrhosis at final TE. In the overall population, using 22.6 kPa as cut-off for cirrhosis, 4 patients had cirrhosis at initial TE and 3 patients had cirrhosis at final TE. There was no statistical difference between initial and final TE in relapsers. In relapsers TE increased in 45% and decreased in 54% of patient. TE decreased significantly during follow-up in 85% of abstinent patients, leading to a modification of the putative fibrosis stage in 28%-71% of patient according to different cut-off value. Eight patients had liver biopsy during follow-up. At the end of the study, 13 (35%) were abstinent, and 24 (65%) relapsers. Thirty-seven patients met our criteria with a median follow-up of 32.5 wk. RESULTS: During the study period 572 patients had TE examination for alcoholic liver disease and 79 of them had at least two examinations. Initial and final putative fibrosis score were compared according to alcohol consumption during follow-up. Putative fibrosis score according to initial and final TE were determined with available cut-off for alcoholic liver disease and hepatitis C. Concomitant biological parameters within 4 wk of initial and final TE were recorded. We retrospectively reviewed file of all patients to include only patient followed up by trained addictologist and for which definite information on alcohol consumption was available. TE examinations with less than ten successful measures or with an interquartile range above 30% were excluded. ![]() TE was performed at least one week apart by senior operator. METHODS: We retrospectively selected in our local database all patients who had two TE between June 2005 and November 2010 with chronic alcohol excessive consumption and excluded those with associated cause of liver disease. AIM: To determine the evolution of transient elastography (TE) in patients with alcoholic liver disease according to alcohol cessation or continuation.
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